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Preferred term

gene-environment interaction  

Definition

  • In the field of epidemiology, there has been increasing interest in documenting the results of interaction between specific genes or genotypes and well-understood environmental exposures. Gene-environment interactions are situations in which the combination of an environmental factor, such as exposure to cigarette smoking, with a genetic factor, such as a disease-predisposing mutation, results in a greater risk or severity of the disease in question than either the genetic or environmental factor acting alone. [Source: Encyclopedia of Epidemiology; Gene-Environment Interaction]

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https://concepts.sagepub.com/social-science/concept/gene-environment_interaction

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