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Preferred term

db/db mouse  

Definition

  • The db/db mouse is a genetically mutated mouse in which leptin receptors do not function properly despite the mouse still being able to produce leptin; This breed of mouse is sometimes referred to as the diabetes mouse. This mouse was first discovered by Jackson Laboratories in 1966 as an obese mouse that ate excessively. [Source: Encyclopedia of Obesity; Db/Db Mouse]

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https://concepts.sagepub.com/social-science/concept/db_db_mouse

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