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Preferred term

missense mutation  

Definition

  • A missense, or nonsynonymous, mutation is a type of point mutation affecting the coding region of a gene which alters a single base such that it codes for a different amino acid. The effects of such a change may be a profound change in phenotype, no perceptible change in phenotype, or some intermediate effect. [Source: Encyclopedia of Global Health; Missense Mutation]

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URI

https://concepts.sagepub.com/social-science/concept/missense_mutation

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